Body building: regulation of shape and size by PI3K/TOR signaling during development
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چکیده
منابع مشابه
Body building: regulation of shape and size by PI3K/TOR signaling during development
Growth of organisms and their constituent parts responds to both intrinsic and extrinsic cues during development: organisms of a given species generally grow at a predictable rate and to a specific body size, but individuals can modify this program during development in response to environmental conditions. Recent experiments, using gene knockouts and targeted overexpression, have revealed the ...
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An amputated cricket leg regenerates all missing parts with normal size and shape, indicating that regenerating blastemal cells are aware of both their position and the normal size of the leg. However, the molecular mechanisms regulating this process remain elusive. Here, we use a cricket model to show that the Dachsous/Fat (Ds/Ft) signalling pathway is essential for leg regeneration. We found ...
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ژورنال
عنوان ژورنال: Mechanisms of Development
سال: 2003
ISSN: 0925-4773
DOI: 10.1016/j.mod.2003.07.003